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[Translation from Japanese to English ] Currently, the intravenous-injection treatment for midazolam is undergoing cl...

[Deleted Account] Translated by [Deleted Account] sujiko Translated by sujiko
[Point]: The Status Epilepticus (convulsive state) is frequently observed for the infants and the elderly. Since there is wide variety of causes, the prognosis depends on the primary disease so that there is no absolute medical treatment due to the complicated factors. If the developed convulsive seizer prolonged longer, it becomes hard to be stopped, and as a result, it may affect the brain development after then. It is the good news that two drugs, the Phenobarbital (Nobelbar®) since December 2009 and the fosphenytoin (Fostin®), have been put into the market as the approved drug labels. Currently, intravenous injection treatment by midazolam is being experimented by Affesa Pharma, in our country. In Eurpoean Union, injection into oral cavity was authorized in September 2011. It is hoped that it will be developed and authorized urgently in our country. At first, status epilepticus is the condition where fit continues longer than certain time, or even if the fit is short , he or she does not come back to be conscious while the fit repeats. It is defined in International League Against Elilepsy 1981.
User's Request Text
「ポイント」・てんかん(けいれん)重積状態は, 乳幼児と高齢者に多い. ・原因は多様であり, 予後は, 基本的に原疾患に左右され, 治療に際しては複雑な要因が関与するので絶対的な方法はない. ・けいれん発作が長く続くほど止まりにくくなり, その後の脳の発達に影響する. ・わが国で2009年12月より静注用フェノバルビタール(ノーベルバール(R)), 2011年12月にフォスフェニトイン(ホストイン(R))が適応承認となったことは福音である. ・現在, ミダゾラムの静注療法はわが国で治験中(アルフレッサファーマ社)である. EUでは2011年9月に口腔内投与が認められた. わが国でも早急な開発・承認が待ち望まれる. 「はじめに」てんかん重積状態(けいれん重積〕は, 「発作がある程度の長さ以上に続くか, または短い発作でも反復しその間意識の回復がないもの」とILAE(International League Against Epilepsy)(1981)で定義されている.

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Japanese=>English

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IT、金融などを中心として社内翻訳者を数年経験後、フリーランス翻訳者として独立。2009年、法人化。得意分野は、法律(契約書、法令、戸籍など)、金融(401Kその他)、不動産(鑑定書、その他)、ホームページ、建築、マーケティング、LED照明、その他。

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