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Twitter is in talks to buy stealth personalization startup Bottlenose for an undisclosed sum, sources close to the matter told Mashable. The companies are said to be in the process of discussing acquisition terms.

Bottlenose, which bills itself as the “the smartest way to personalize and filter Twitter,” hails from serial startup founders Dominiek ter Heide and Nova Spivack. The startup created a Twitter account and splash page in late August but is keeping the site on lockdown until early spring 2011. Bottlenose automatically surfaces important information, tracks a user’s interests, visualizes trends and curates knowledge between friends. It sounds like a cross between Cadmus and Summify with a few bonus features.

Twitter, now keen on helping users personalize their information network experience through interests, enhanced its search tool Monday with topic-driven suggestions of people and accounts for users to follow. A new homepage with a “follow your interests” tagline is also being rolled out to users. Bottlenose could provide Twitter with a missing piece to the personalization puzzle and finally give users a native way to discover important tweets, matching their interests, that they otherwise would have overlooked or lost in their real-time tweet stream.