Translator Reviews ( Japanese → English )

Rating: 44 / 0 Reviews / 13 May 2012 at 00:25

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Japanese

パーキンソン病は,脳のなかでドーパミンを分泌するニューロンが死滅することによって生じる。手足がふるえる,体がこわばるといった症状の出るこの病気の治療の第一選択は,L-ドーパをはじめとする薬物療法(DBS)だ。最近では脳の深部に電極を刺し,胸部に埋め込んだパルス発生器からの信号で刺激する治療法もあり,80%以上の症例で症状が改善するか薬の量を減らせるようになっている。 ところが,これらの方法で症状は改善できても,ドーパミン産生ニューロンが死んでいくのを食い止めることはできない。

English

Parkinson's disease is caused by the death of dopamine-generating neurons in a brain. The primary treatment for this disease with the symptoms of tremors of limbs and rigidity of body is a drug treatment such as L-dopa. Recently DBS (Deep Brain Stimulation) has been introduced to electrically stimulate the deep inside the brain by implanting a pulse generator inside the chest and an electrode in the brain. This has been helping reducing the drug intake amount or alleviating 80 percent of the symptoms of the patients. While these may be helping with the symptoms, however, they cannot stop the dopamine-generating nerons death.

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